Feedback regulation via AMPK and HIF-1 mediates ROS-dependent...
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AMPK mediates ROS-induced longevity. (A – E) Paraquat (0.25 mM) treatment increased the lifespan of wild-type animals. This lifespan extension was suppressed by mutations in genes encoding AMPK pathway components, including aak-2 (ok524) (A and B), aak-2 (rr48) (C), aakb-2 (rr88) (D), and par-4 (tm2986) (E). (F) Percent changes in the lifespan of various C. elegans mutants upon 0.25 mM ...rr88 com
The aims of this study were, first, to identify current forms of school-based sexual health services (SBSHS) and school-linked sexual health services (SLSHS) in the UK; second, to review and synthesise existing evidence from qualitative and